Propofol, introduced into clinical practice in 1986, produces rapid smooth induction of anesthesia and the emergence from propofol anesthesia is rapid than that from thiopental with minimal residual effects. Thus the properties of rapid induction
and
emergence making it a popular agent in short operations especially in day-case surgery, and suitable for TIVA.
We compared the effects of intravenous anesthesia of propofol and fentanyl with that of inhalational enflurane anesthesia on cardiopulmonary, hepato-renal functins and alterations of emergence from anesthesia, in 32 cases of laparoscopic
cholecystectomy.
The results were the following. The propofol group. systemic arterial blood pressure was decreased immediately following the induction but in enflurane group, that was increased transiently following the tracheal intubation and then mainteined
preinduction levels. Propofol decreased heart rate generally, while inhalation anesthesia with enflurane increased it transiently following the tracheal intubationand then maintained stable state. The PaCO2 was increased at 30 min after recovery
room
arrival inboth groups. The total bilirubin, direct bilirubin, SGOT and SGPT were increased postoperatively, but protein, albumin and BUN levels were decreased. Emergence and recovery time in propofol group were statistically shorter than
enflurane
group. There are no specific complications in both groups.
In conclusion, balanced anesthesia with propofol and fentanyl was considered to have good controllability nearly equal to inhalational anesthesia with enflurane, so balanced anesthesia can be carry the laparoscopic cholecystectomy instead of
inhaled
anesthesia.
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